Comparing the effectiveness of intra articular hyaluronic acid injection and intra articular corticosteroid injection in symptomatic osteoarthritis knee

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Intra-articular corticosteroid injection for osteoarthritis

Efficacy Intra-articular corticosteroid injection is quick and simple to carry out and in RCTs it has a large effect size (ES) of 1.27 at 7 days postinjection for pain relief against placebo for knee OA [101]. It produces relatively rapid relief of severe pain within a few hours or days. Although this benefit is relatively short lasting, in RCTs (1–4 weeks), individual patients may derive benef...

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Efficacy of Intra-Articular Injection of Hyaluronic Acid in the Treatment of Knee Osteoarthritis

This study was conducted to evaluate the efficacy of intraarticular injection of hyaluronic acid for the treatment of knee osteoarthritis. Patients with knee osteoarthritis were followed for a period of six months to assess the efficacy of intra-articular injection of hyaluronic acid given three times in three consecutive weeks. Fifty patients were reviewed at two, eight and 24 weeks post-injec...

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Effect of intra-articular injection of hyaluronic acid in rheumatoid arthritis patients with knee osteoarthritis.

BACKGROUND Intra-articular injection of hyaluronic acid (HA) is a well-documented treatment for knee osteoarthritis (OA). One of the multifactorial mechanisms is that exogenous HA can stimulate endogenous HA production. HA can regulate the growth and function of chondrocytes by binding to CD44 receptors on the chondrocytes. Synovitis is often found in patients with rheumatoid arthritis (RA) and...

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Therapeutic trajectory following intra-articular hyaluronic acid injection in knee osteoarthritis--meta-analysis.

OBJECTIVE To evaluate the therapeutic trajectory of intra-articular hyaluronic acid (IAHA) vs placebo for knee osteoarthritis (OA). DESIGN Our data sources include Medline, EMBASE, CINAHL, BIOSIS, Web of Science, Google Scholar, Cochrane database; hand searched reviews, manuscripts, and, supplements; author contacts for unpublished data. Randomized trials that reported effects of IAHA vs plac...

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Intra-articular corticosteroid for knee osteoarthritis.

BACKGROUND Knee osteoarthritis is a leading cause of chronic pain, disability, and decreased quality of life. Despite the long-standing use of intra-articular corticosteroids, there is an ongoing debate about their benefits and safety. This is an update of a Cochrane review first published in 2005. OBJECTIVES To determine the benefits and harms of intra-articular corticosteroids compared with...

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ژورنال

عنوان ژورنال: International Journal of Orthopaedics Sciences

سال: 2018

ISSN: 2395-1958,2395-1958

DOI: 10.22271/ortho.2018.v4.i4i.84